Bioserf Help Page


BioSerf is our new, experimental, fully automated, ab initio homology modelling pipeline available via the World Wide Web or as an XML driven webservice (manuscript in preparation). BioSerf uses a selection of algorithms including PSI-BLAST, PSIPRED and pGenTHREADER to attempt to select appropriate template structures for homology modelling. Where a suitable template or templates can not be found BioSerf uses Modeller to build a model. Where no suitable template structure can be found FRAGFOLD is used to build a model (see figure below). As this service uses Modeller, a valid modeller licence key is required to submit sequences to the service.